Tag Archives: Acral lentiginous melanoma


Melanoma Cancer: Causes and Risk Factors


Melanoma is the most dangerous type of skin cancer. It is the leading cause of death from skin disease. Currently it is the sixth most common cancer in both males and females.


What is the cause and incidence of melanoma?

The melanoma develop when unrepaired DNA damage to skin cells (most often caused by ultraviolet radiation from sunshine or tanning beds) triggers mutations (genetic defects) that causes the skin cells to multiply rapidly and form malignant tumors.  These tumors originate in the pigment-producing melanocytes in the basal layer of the epidermis. Melanomas often resemble moles; some develop from moles. The majority of melanomas are black or brown, but they can also be skin-colored, pink, red, purple, blue or white. Melanoma is caused mainly by intense, occasional UV exposure (frequently leading to sunburn), especially in those who are genetically predisposed to the disease. Melanoma kills an estimated 8,790 people in the US annually. Continue reading